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C 3 Nephritic Factor

《英文msh詞典》C 3 Nephritic Factor
[入口詞] C 3 Nephritic Factor
[主題詞] Complement 3 Nephritic Factor
[英文釋義] A magnesium-dependent IMMUNOGLOBULIN G autoantibody found in serum of patients with chronic mesangioproliferative hypocomplementemic glomerulonephritis. It causes inactivation of C3 in the alternate pathway by cleaving C3 into two inactive fragments,C3c and C3d,instead of the normal C3b.